This short article shows you why Open with Access is not working in Office 365 SharePoint or SharePoint Online 2013 when you are working with SharePoint List.
If you are using Google Chrome, you cannot even see Open with Access.
If you are using Microsoft Edge then you with see the Open with Access feature is disable.
The only browser that can work with Open with Access feature for the moment is IE 11.
It is really not a good idea to use Chrome with SharePoint Online.